A large family of Dscam genes with tandemly arrayed 5′ cassettes in Chelicerata

Yuan Yue; Yijun Meng; Hongru Ma; Shouqing Hou; Guozheng Cao; Weiling Hong; Yang Shi; Pengjuan Guo; Baoping Liu; Feng Shi; Yun Yang; Yongfeng Jin

doi:10.1038/ncomms11252

Nature Communications (Apr 2016)

A large family of Dscam genes with tandemly arrayed 5′ cassettes in Chelicerata

Yuan Yue,
Yijun Meng,
Hongru Ma,
Shouqing Hou,
Guozheng Cao,
Weiling Hong,
Yang Shi,
Pengjuan Guo,
Baoping Liu,
Feng Shi,
Yun Yang,
Yongfeng Jin

Affiliations

Yuan Yue: Institute of Biochemistry, Innovation Center for Signaling Network, College of Life Sciences, Zhejiang University
Yijun Meng: College of Life and Environmental Sciences
Hongru Ma: Institute of Biochemistry, Innovation Center for Signaling Network, College of Life Sciences, Zhejiang University
Shouqing Hou: Institute of Biochemistry, Innovation Center for Signaling Network, College of Life Sciences, Zhejiang University
Guozheng Cao: Institute of Biochemistry, Innovation Center for Signaling Network, College of Life Sciences, Zhejiang University
Weiling Hong: Institute of Biochemistry, Innovation Center for Signaling Network, College of Life Sciences, Zhejiang University
Yang Shi: Institute of Biochemistry, Innovation Center for Signaling Network, College of Life Sciences, Zhejiang University
Pengjuan Guo: Institute of Biochemistry, Innovation Center for Signaling Network, College of Life Sciences, Zhejiang University
Baoping Liu: Institute of Biochemistry, Innovation Center for Signaling Network, College of Life Sciences, Zhejiang University
Feng Shi: Institute of Biochemistry, Innovation Center for Signaling Network, College of Life Sciences, Zhejiang University
Yun Yang: Institute of Biochemistry, Innovation Center for Signaling Network, College of Life Sciences, Zhejiang University
Yongfeng Jin: Institute of Biochemistry, Innovation Center for Signaling Network, College of Life Sciences, Zhejiang University

DOI: https://doi.org/10.1038/ncomms11252
Journal volume & issue: Vol. 7, no. 1
pp. 1 – 12

Abstract

Read online

Drosophila Dscam1 and vertebrate clustered protocadherins (Pcdh) are known for their extraordinary isoform diversity. Here authors identify a shortened Dscam gene family in Chelicerata, which displays homology to Drosophila Dscam1, and employs splicing patterns similar to that of vertebrate Pcdhs.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

About the journal