Isolamento, identificazione e sensibilità ai farmaci antimicrobici di due ceppi di Mycobacterium marinum da fish tank granuloma

Abstract

Mycobacterium marinum is an emerging pathogen responsible for cutaneous infections related to the handling of domestic aquariums.Two distinct strains of M. marinum have been isolated from as many cases of fish tank granuloma. Despite the ability of both strains to grow at 37° C, the detection of their growth by the automated BACTEC 9000MB system, was delayed or not happened at all in comparison with the growth of mycobacterium culture in the Löwenstein-Jensen medium.The different antibiotic susceptibility pattern showed by M. marinum in several studies, required to perform suscepibility testing of two clinical isolates. Both strains were resistant to isoniazid, imipenem, cefoxitine, susceptible to rifampicin, ethambutol, clarithromycin, ciprofloxacin and moderately susceptible to doxycycline.

Keywords

• Mycobacterium marinum, fish tank granuloma, drug-sucepibility testing