Motionless volumetric photoacoustic microscopy with spatially invariant resolution

Jiamiao Yang; Lei Gong; Xiao Xu; Pengfei Hai; Yuecheng Shen; Yuta Suzuki; Lihong V. Wang

doi:10.1038/s41467-017-00856-2

Nature Communications (Oct 2017)

Motionless volumetric photoacoustic microscopy with spatially invariant resolution

Jiamiao Yang,
Lei Gong,
Xiao Xu,
Pengfei Hai,
Yuecheng Shen,
Yuta Suzuki,
Lihong V. Wang

Affiliations

Jiamiao Yang: Caltech Optical Imaging Laboratory, Andrew and Peggy Cherng Department of Medical Engineering, Department of Electrical Engineering, California Institute of Technology
Lei Gong: Optical Imaging Laboratory, Department of Biomedical Engineering, Washington University in St Louis
Xiao Xu: Optical Imaging Laboratory, Department of Biomedical Engineering, Washington University in St Louis
Pengfei Hai: Caltech Optical Imaging Laboratory, Andrew and Peggy Cherng Department of Medical Engineering, Department of Electrical Engineering, California Institute of Technology
Yuecheng Shen: Caltech Optical Imaging Laboratory, Andrew and Peggy Cherng Department of Medical Engineering, Department of Electrical Engineering, California Institute of Technology
Yuta Suzuki: Optical Imaging Laboratory, Department of Biomedical Engineering, Washington University in St Louis
Lihong V. Wang: Caltech Optical Imaging Laboratory, Andrew and Peggy Cherng Department of Medical Engineering, Department of Electrical Engineering, California Institute of Technology

DOI: https://doi.org/10.1038/s41467-017-00856-2
Journal volume & issue: Vol. 8, no. 1
pp. 1 – 7

Abstract

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Photoacoustic microscopy allows for label-free 3D in vivo imaging by detecting the acoustic response of a photoexcited material. Here, Yang et. al use a digital-micromirror-device based structured illumination scheme to both improve resolution and greatly increase the depth of field, enabling 3D volumetric imaging.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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