Frontiers in Neurology (Apr 2021)

Snoring Is Associated With Increased Risk of Stroke: A Cumulative Meta-Analysis

  • Jing Bai,
  • Bing He,
  • Nan Wang,
  • Yifei Chen,
  • Yifei Chen,
  • Junxiang Liu,
  • Haoran Wang,
  • Dongliang Liu

DOI
https://doi.org/10.3389/fneur.2021.574649
Journal volume & issue
Vol. 12

Abstract

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Background: Several studies have suggested that snoring is associated with an increased risk of stroke; however, the results are inconsistent. We aim to conduct a systematic review and meta-analysis of observational studies assessing the association between snoring and the risk of stroke in adults.Methods: We searched PubMed for relevant studies. A random-effect model was adopted to summary relative risks (RRs), and forest plots from a cumulative meta-analysis method were used for a better presentation of how the pooled RRs changed as updated evidence accumulated.Results: The literature search yielded 16 articles that met our inclusion criteria, and a total of 3,598 stroke patients and 145,901 participants were finally included in our analysis. A consistent trend toward association was found after the initial discovery, and the summary analysis indicated that snoring is associated with a 46% (RR, 1.46; 95%CI, 1.29–1.63; p < 0.001) increased risk of stroke.Conclusions: Snoring is associated with a significantly increased risk for stroke, up to 46%. The importance of the current study lies in that we provide an imputes to take a more active approach against the increased risk of stroke in snorers.

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