Synthesis and antimicrobial activity of a new series of 1,4-dihydropyridine derivatives

Abstract

A series of 1,4-dihydropyridine derivatives (1a–g) were prepared from Hantzsch syntheses. The compounds 1a–g were reacted with thiosemicarbazide to give the new series of compounds 2a–g. IR, 1H-NMR, 13C-NMR, mass spectral and elemental analysis confirmed the synthesized compounds. The synthesized compounds were also screened for their antimicrobial activity.

Keywords

• 1
• 4-dihydropyridine
• thiosemicarbazide
• condensation
• antimicrobial activity