Nature Communications (Jan 2023)
Rapidly shifting immunologic landscape and severity of SARS-CoV-2 in the Omicron era in South Africa
- Kaiyuan Sun,
- Stefano Tempia,
- Jackie Kleynhans,
- Anne von Gottberg,
- Meredith L. McMorrow,
- Nicole Wolter,
- Jinal N. Bhiman,
- Jocelyn Moyes,
- Maimuna Carrim,
- Neil A. Martinson,
- Kathleen Kahn,
- Limakatso Lebina,
- Jacques D. du Toit,
- Thulisa Mkhencele,
- Cécile Viboud,
- Cheryl Cohen,
- the PHIRST-C group
Affiliations
- Kaiyuan Sun
- Division of International Epidemiology and Population Studies, Fogarty International Center, National Institutes of Health
- Stefano Tempia
- Centre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases of the National Health Laboratory Service
- Jackie Kleynhans
- Centre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases of the National Health Laboratory Service
- Anne von Gottberg
- Centre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases of the National Health Laboratory Service
- Meredith L. McMorrow
- COVID-19 Response, Centers for Disease Control and Prevention
- Nicole Wolter
- Centre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases of the National Health Laboratory Service
- Jinal N. Bhiman
- Centre for HIV and STIs, National Institute for Communicable Diseases of the National Health Laboratory Service
- Jocelyn Moyes
- Centre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases of the National Health Laboratory Service
- Maimuna Carrim
- Centre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases of the National Health Laboratory Service
- Neil A. Martinson
- Perinatal HIV Research Unit, University of the Witwatersrand
- Kathleen Kahn
- MRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), School of Public Health, Faculty of Health Sciences, University of the Witwatersrand
- Limakatso Lebina
- Perinatal HIV Research Unit, University of the Witwatersrand
- Jacques D. du Toit
- MRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), School of Public Health, Faculty of Health Sciences, University of the Witwatersrand
- Thulisa Mkhencele
- Centre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases of the National Health Laboratory Service
- Cécile Viboud
- Division of International Epidemiology and Population Studies, Fogarty International Center, National Institutes of Health
- Cheryl Cohen
- Centre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases of the National Health Laboratory Service
- the PHIRST-C group
- DOI
- https://doi.org/10.1038/s41467-022-35652-0
- Journal volume & issue
-
Vol. 14,
no. 1
pp. 1 – 13
Abstract
Emergence of the Omicron BA.1/2 SARS-CoV-2 subvariants led to a wave of infection South Africa. Here, the authors use serological data from a prospective household study to characterise infection rates in the context of diverse immune histories following vaccination and exposure to different variants.
