Frontiers in Immunology (Oct 2022)
Immune-related arthritis following pelvic radiation therapy in a patient with lung cancer receiving long-term immune checkpoint blocker treatment: Case report
- Mihaela Aldea,
- Rakiba Belkhir,
- Emeline Colomba,
- Pierre Blanchard,
- Francois-Xavier Danlos,
- Angela Botticella,
- Mario Terlizzi,
- Eric Deutsch,
- Eric Deutsch,
- Cecile Le Péchoux,
- David Planchard,
- Jean-Marie Michot,
- Benjamin Besse,
- Antonin Levy,
- Antonin Levy
Affiliations
- Mihaela Aldea
- Department of Medical Oncology, International Center for Thoracic Cancers (CICT), Université Paris-Saclay, Gustave Roussy, Villejuif, France
- Rakiba Belkhir
- Rheumatology, Hôpital Bicêtre, Assistance Publique-Hôpitaux de Paris, FHU CARE, Le Kremlin-Bicêtre, France
- Emeline Colomba
- Department of Medical Oncology, International Center for Thoracic Cancers (CICT), Université Paris-Saclay, Gustave Roussy, Villejuif, France
- Pierre Blanchard
- Department of Radiation Oncology, International Center for Thoracic Cancers (CICT), Université Paris-Saclay, Gustave Roussy, Villejuif, France
- Francois-Xavier Danlos
- Department of Medical Oncology, International Center for Thoracic Cancers (CICT), Université Paris-Saclay, Gustave Roussy, Villejuif, France
- Angela Botticella
- Department of Radiation Oncology, International Center for Thoracic Cancers (CICT), Université Paris-Saclay, Gustave Roussy, Villejuif, France
- Mario Terlizzi
- Department of Radiation Oncology, International Center for Thoracic Cancers (CICT), Université Paris-Saclay, Gustave Roussy, Villejuif, France
- Eric Deutsch
- Department of Radiation Oncology, International Center for Thoracic Cancers (CICT), Université Paris-Saclay, Gustave Roussy, Villejuif, France
- Eric Deutsch
- INSERM U1030, Molecular Radiotherapy, Université Paris-Saclay, Villejuif, France
- Cecile Le Péchoux
- Department of Radiation Oncology, International Center for Thoracic Cancers (CICT), Université Paris-Saclay, Gustave Roussy, Villejuif, France
- David Planchard
- Department of Medical Oncology, International Center for Thoracic Cancers (CICT), Université Paris-Saclay, Gustave Roussy, Villejuif, France
- Jean-Marie Michot
- DITEP (Département des Innovations Thérapeutiques et Essais Précoces), Université Paris-Saclay, Gustave Roussy, Villejuif, France
- Benjamin Besse
- Department of Medical Oncology, International Center for Thoracic Cancers (CICT), Université Paris-Saclay, Gustave Roussy, Villejuif, France
- Antonin Levy
- Department of Radiation Oncology, International Center for Thoracic Cancers (CICT), Université Paris-Saclay, Gustave Roussy, Villejuif, France
- Antonin Levy
- INSERM U1030, Molecular Radiotherapy, Université Paris-Saclay, Villejuif, France
- DOI
- https://doi.org/10.3389/fimmu.2022.920130
- Journal volume & issue
-
Vol. 13
Abstract
Radiotherapy can trigger immune-related out-of-field “abscopal” response. We report a patient with advanced NSCLC (non-small cell lung cancer) receiving long-term anti-PD1 (programmed cell death protein 1) who have developed out-of-field immune-related arthritis following pelvic irradiation.
Keywords
