Frontiers in Immunology (Oct 2021)
The Omic Insights on Unfolding Saga of COVID-19
- Arvinpreet Kaur,
- Arvinpreet Kaur,
- Mehak Chopra,
- Mahak Bhushan,
- Sonal Gupta,
- Sonal Gupta,
- Hima Kumari P,
- Narmadhaa Sivagurunathan,
- Nidhi Shukla,
- Nidhi Shukla,
- Shalini Rajagopal,
- Purva Bhalothia,
- Purnima Sharma,
- Jalaja Naravula,
- Renuka Suravajhala,
- Renuka Suravajhala,
- Ayam Gupta,
- Bilal Ahmed Abbasi,
- Prittam Goswami,
- Harpreet Singh,
- Harpreet Singh,
- Rahul Narang,
- Rathnagiri Polavarapu,
- Krishna Mohan Medicherla,
- Jayaraman Valadi,
- Jayaraman Valadi,
- Anil Kumar S,
- Gyaneshwer Chaubey,
- Keshav K. Singh,
- Obul Reddy Bandapalli,
- Obul Reddy Bandapalli,
- Obul Reddy Bandapalli,
- Polavarapu Bilhan Kavi Kishor,
- Polavarapu Bilhan Kavi Kishor,
- Prashanth Suravajhala,
- Prashanth Suravajhala,
- Prashanth Suravajhala
Affiliations
- Arvinpreet Kaur
- Department of Bioinformatics, Hans Raj Mahila Maha Vidyalaya, Punjab, India
- Arvinpreet Kaur
- Bioclues.org, Hyderabad, India
- Mehak Chopra
- Centre for Bioinformatics, School of Life Sciences, Pondicherry University, Puducherry, India
- Mahak Bhushan
- Department of Biological Sciences, Indian Institute of Science Education and Research, Kolkata, India
- Sonal Gupta
- Bioclues.org, Hyderabad, India
- Sonal Gupta
- Department of Biotechnology and Bioinformatics, Birla Institute of Scientific Research, Jaipur, India
- Hima Kumari P
- Bioclues.org, Hyderabad, India
- Narmadhaa Sivagurunathan
- Department of Biotechnology and Bioinformatics, Birla Institute of Scientific Research, Jaipur, India
- Nidhi Shukla
- Bioclues.org, Hyderabad, India
- Nidhi Shukla
- Department of Biotechnology and Bioinformatics, Birla Institute of Scientific Research, Jaipur, India
- Shalini Rajagopal
- Vignan’s Foundation for Science, Technology & Research (Deemed to be University), Guntur, India
- Purva Bhalothia
- Department of Biotechnology and Bioinformatics, Birla Institute of Scientific Research, Jaipur, India
- Purnima Sharma
- Department of Bioinformatics, Hans Raj Mahila Maha Vidyalaya, Punjab, India
- Jalaja Naravula
- Vignan’s Foundation for Science, Technology & Research (Deemed to be University), Guntur, India
- Renuka Suravajhala
- Bioclues.org, Hyderabad, India
- Renuka Suravajhala
- Department of Chemistry, School of Basic Sciences, Manipal University Jaipur, Jaipur, India
- Ayam Gupta
- Vignan’s Foundation for Science, Technology & Research (Deemed to be University), Guntur, India
- Bilal Ahmed Abbasi
- Functional Genomics Unit, Council of Scientific and Industrial Research- Institute of Genomics & Integrative Biology (CSIR-IGIB), Delhi, India
- Prittam Goswami
- Department of Biotechnology, Haldia Institute of Technology, West Bengal, India
- Harpreet Singh
- Department of Bioinformatics, Hans Raj Mahila Maha Vidyalaya, Punjab, India
- Harpreet Singh
- Bioclues.org, Hyderabad, India
- Rahul Narang
- 0Department of Microbiology, All India Institute of Medical Sciences, Bibinagar, Hyderabad, India
- Rathnagiri Polavarapu
- 1Genomix CARL Pvt. Ltd, Pulivendula, India
- Krishna Mohan Medicherla
- Department of Biotechnology and Bioinformatics, Birla Institute of Scientific Research, Jaipur, India
- Jayaraman Valadi
- Bioclues.org, Hyderabad, India
- Jayaraman Valadi
- 2Department of Computer Science, Flame University, Pune, India
- Anil Kumar S
- Vignan’s Foundation for Science, Technology & Research (Deemed to be University), Guntur, India
- Gyaneshwer Chaubey
- 3Cytogenetics Laboratory, Department of Zoology, Benaras Hindu University, Varanasi, India
- Keshav K. Singh
- 4Department of Genetics, University of Alabama, Birmingham, AL, United States
- Obul Reddy Bandapalli
- Bioclues.org, Hyderabad, India
- Obul Reddy Bandapalli
- 5German Cancer Research Centre (DKFZ), Heidelberg, Germany
- Obul Reddy Bandapalli
- 6Department of Applied Biology, Council of Scientific and Industrial Research-Indian Institute of Chemical Technology (CSIR-IICT), Hyderabad, India
- Polavarapu Bilhan Kavi Kishor
- Bioclues.org, Hyderabad, India
- Polavarapu Bilhan Kavi Kishor
- Vignan’s Foundation for Science, Technology & Research (Deemed to be University), Guntur, India
- Prashanth Suravajhala
- Bioclues.org, Hyderabad, India
- Prashanth Suravajhala
- Department of Biotechnology and Bioinformatics, Birla Institute of Scientific Research, Jaipur, India
- Prashanth Suravajhala
- 7Amrita School of Biotechnology, Amrita Vishwa Vidyapeetham, Kerala, India
- DOI
- https://doi.org/10.3389/fimmu.2021.724914
- Journal volume & issue
-
Vol. 12
Abstract
The year 2019 has seen an emergence of the novel coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing coronavirus disease of 2019 (COVID-19). Since the onset of the pandemic, biological and interdisciplinary research is being carried out across the world at a rapid pace to beat the pandemic. There is an increased need to comprehensively understand various aspects of the virus from detection to treatment options including drugs and vaccines for effective global management of the disease. In this review, we summarize the salient findings pertaining to SARS-CoV-2 biology, including symptoms, hosts, epidemiology, SARS-CoV-2 genome, and its emerging variants, viral diagnostics, host-pathogen interactions, alternative antiviral strategies and application of machine learning heuristics and artificial intelligence for effective management of COVID-19 and future pandemics.
Keywords
