mBio
(Apr 2021)
Longitudinal Multi-omics and Microbiome Meta-analysis Identify an Asymptomatic Gingival State That Links Gingivitis, Periodontitis, and Aging
Shi Huang,
Tao He,
Feng Yue,
Xiujun Xu,
Lijiang Wang,
Pengfei Zhu,
Fei Teng,
Zheng Sun,
Xiaohui Liu,
Gongchao Jing,
Xiaoquan Su,
Lijian Jin,
Jiquan Liu,
Jian Xu
Affiliations
Shi Huang
Single-Cell Center, Qingdao Institute of BioEnergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, Shandong, China
Tao He
Procter & Gamble Company, Global Oral Care Clinical Operations, Mason, Ohio, USA
Feng Yue
Procter & Gamble Innovation Center, Beijing, China
Xiujun Xu
Procter & Gamble Innovation Center, Beijing, China
Lijiang Wang
Procter & Gamble Innovation Center, Beijing, China
Pengfei Zhu
Single-Cell Center, Qingdao Institute of BioEnergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, Shandong, China
Fei Teng
Single-Cell Center, Qingdao Institute of BioEnergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, Shandong, China
Zheng Sun
Single-Cell Center, Qingdao Institute of BioEnergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, Shandong, China
Xiaohui Liu
School of Life Sciences, Tsinghua University, Beijing, China
Gongchao Jing
Single-Cell Center, Qingdao Institute of BioEnergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, Shandong, China
Xiaoquan Su
ORCiD
Single-Cell Center, Qingdao Institute of BioEnergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, Shandong, China
Lijian Jin
ORCiD
Faculty of Dentistry, The University of Hong Kong, Hong Kong SAR, China
Jiquan Liu
Procter & Gamble Innovation Center, Beijing, China
Jian Xu
ORCiD
Single-Cell Center, Qingdao Institute of BioEnergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, Shandong, China
DOI
https://doi.org/10.1128/mBio.03281-20
Journal volume & issue
Vol. 12,
no. 2
Abstract
Read online
A significant portion of world population still fails to brush teeth daily. As a result, the majority of the global adult population is afflicted with chronic gingivitis, and if it is left untreated, some of them will eventually suffer from periodontitis.
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