International Journal of COPD (Jul 2022)

Evaluating the Relationship of Airflow Obstruction in COPD with Severity of OSA Among Patients with Overlap Syndrome

  • Stewart NH,
  • Brittan M,
  • McElligott M,
  • Summers MO,
  • Samson K,
  • Press VG

Journal volume & issue
Vol. Volume 17
pp. 1613 – 1621

Abstract

Read online

Nancy H Stewart,1 Mollie Brittan,2 Maureen McElligott,2 Michael O Summers,2 Kaeli Samson,3 Valerie G Press4 1Department of Medicine, University of Kansas Medical Center, Kansas City, KS, USA; 2Department of Medicine, University of Nebraska Medical Center, Omaha, NE, USA; 3Department of Biostatistics, University of Nebraska Medical Center, Omaha, NE, USA; 4Department of Medicine, University of Chicago Medical Center, Chicago, IL, USACorrespondence: Nancy H Stewart, Department of Medicine, University of Kansas Medical Center, 3901 Rainbow Blvd, Kansas City, KS, 66160, USA, Email [email protected]: Chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) are common diseases affecting millions worldwide. These two diseases have a complex relationship that is not well understood. Previous small studies suggest an inverse relationship of disease severity of OSA with COPD airflow obstruction.Objective: The aim of this study was to determine if a relationship exists between severity of airflow obstruction in COPD and severity of OSA via apnea hypopnea index obtained during an in-lab baseline polysomnogram using a large quaternary care center cohort.Methods: From November 2015 through December 2018, 273 patients with confirmed COPD via spirometry and OSA via in-lab baseline polysomnogram were included.Conclusion: No associations were noted between severity of airflow obstruction in COPD and disease severity of OSA. Given the heterogeneity of these diseases, further exploration of a relationship within disease subtypes is warranted.Keywords: airflow obstruction, chronic obstructive pulmonary disease, obstructive sleep apnea

Keywords