Analysis of risk factors of enterostomy in infants with Hirschsprung's disease

Abstract

Objective To explore the risk factors of enterostomy in infants with Hirschsprung' s disease (HSCR) to facilitate timely evaluation of the condition and the clinical decision-making on the timing of intervention. Methods We retrospectively analyzed the data of 201 infants diagnosed with HSCR in our hospital between January, 2013 and January, 2019. Univariate analysis and multivariate logistic regression were used to analyze the clinical data and laboratory test results of the patients to identify the risk factors of enterostomy. Results The incidence of enterostomy was 22.4% in these infants. Multivariate logistic regression analysis showed that lowered serum albumin level (OR = 0. 737, 95% CI: 0. 633 - 0. 857, P = 0. 000), abnormal stool routine (OR = 10. 634, 95% CI: 3. 016-37. 502, P = 0. 000), procalcitonin (PCT) level >2 ng /mL (OR = 9. 954, 95% CI: 2. 517-39. 368, P = 0. 001), and right-sided HSCR (OR = 4. 307, 95% CI: 1. 417-13. 092, P = 0. 010) were risk factors for enterostomy in infants. Conclusion A lowed serum albumin level, abnormal stool routine, a PCT level > 2 ng /mL and right-sided HSCR are risk factors for enterostomy in infants with HSCR.

Keywords

• hirschsprung's disease
• enterostomy
• risk factors
• infants