Profiling triglyceride-glucose index in Filipinos with type 2 diabetes mellitus: a single-center study

Abstract

Abstract Background In this study, we evaluated the utility of the TyG index among Filipino patients with type 2 diabetes mellitus (T2DM) and explored its association with various laboratory markers. Methods An analytical cross-sectional study was conducted by retrospectively obtaining data from the medical records of 109 Filipino T2DM patients from a tertiary level teaching hospital. Data obtained were then statistically analyzed. Results Results revealed an overall TyG index of 9.15 ± 0.71 among the participants. A significant dose-response relationship was observed between the TyG index and HbA1c. The AUC result has an acceptable discriminating ability among patients with varying glycemic control. The optimal cut-off value of >8.4 has a sensitivity of 92.5% and a specificity of 47.1% in identifying patients with poor glycemic control. Conclusion Overall, our findings show the potential of TyG index in glycemic control assessment among Filipinos with T2DM. However, further analysis must be performed to verify its clinical utility and applicability in different populations.

Keywords

• Triglyceride-glucose index
• Type 2 diabetes mellitus
• Filipino
• Glycemic control
• HbA1c
• AUC