ETHNIC FEATURES OF BLOOD LIPID PROFILE IN SIBERIANS AGED 60–69 YEARS

Abstract

Aim. To study potential specific features of blood lipid profile in elderly indigenous and non-indigenous Yakutsk City residents, as well as in elderly Caucasian residents of Novosibirsk City.Material and methods. The representative sample of the non-institutionalised Yakutsk City population aged 60–69 years (main group, MG) included 159 people (69 men and 90 women; 41% of indigenous (Yakut) ethnicity and 59% of Caucasian ethnicity). The comparison group (CG) included 3949 Novosibirsk City residents who were participating in the international HAPIEE study (1834 men and 2115 women; 96% of Caucasian ethnicity).Results. The age-standardised blood lipid levels were similar in indigenous and non-indigenous Yakutsk City residents. The mean levels of total cholesterol (TCH) were 5,9 mmol/l in the whole sample, 5,8 mmol/l in men, and 6,1% mmol/l in women. In Yakut participants, these figures were 5,8, 5,7, and 5,9 mmol/l, respectively, while in Russian participants, they were slightly higher (6,0, 5,8, and 6,2 mmol/l, respectively). The levels of non-high density and low density lipoprotein cholesterol (nonHDL CH, LDL–CH) demonstrated similar gender and ethnic features. In non-indigenous Yakutsk City residents, the levels of TCH, LDL–CH, and high-density lipoprotein cholesterol (HDL–CH) were significantly lower than those in Novosibirsk City residents: 6,0 vs. 6,44 mmol/l for TCH (p<0,01); 3,9 vs. 4,2 mmol/l (p<0,01) for LDL–CH; and 1,44 vs. 1,52 mmol/l (p<0,05) for HDL–CH, respectively.Conclusion. In elderly indigenous residents of Yakutsk City, the levels of TCH, LDL–CH, non-HDL–CH, and triglycerides were slightly lower than those in non-indigenous Yakutsk City residents. In non-indigenous Yakutsk City residents, aged 60–69, the levels of TCH, non-HDL–CH, LDL–CH, and HDL–CH were lower than in their peers from Novosibirsk City.

Keywords

• липиды крови
• пожилые
• популяционное исследование