Clinical Case Reports (Apr 2024)

Subacute thyroiditis after SARS‐CoV‐2 vaccination: A case report

  • Ozra Akha,
  • Mahdi Mazandarani,
  • Soroush Azari,
  • Niloofar Daneshfar,
  • Kimia Rasouli,
  • Keyvan Heydari,
  • Golvash Tavakolian,
  • Aref Hoseini

DOI
https://doi.org/10.1002/ccr3.8678
Journal volume & issue
Vol. 12, no. 4
pp. n/a – n/a

Abstract

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Key Clinical Message Subacute thyroiditis which is typically characterized by cervical pain and fever is caused by viral infection and is seen after SARS‐CoV‐2 vaccination. Here we report a post‐vaccination subacute thyroiditis after SARS‐CoV‐2 vaccination. Abstract Subacute thyroiditis (SAT) is possibly caused by a viral infection and is typically characterized by cervical pain and fever. SAT associated with SARS‐CoV‐2 infection or SARS‐CoV‐2 vaccination has been reported, albeit in limited numbers. A 34‐year‐old woman was referred to our clinic with typical SAT symptoms. The diagnosis was confirmed through thyroid scintigraphy after receiving the SARS‐CoV‐2 vaccination, despite testing negative for COVID‐19 via RT‐PCR. There is a theoretical correlation between SARS‐CoV‐2 vaccination and SAT. Vaccination may have a direct or indirect impact on the thyroid, but further studies are required to confirm this relationship. A systematic review of the literature of similar cases was performed for comparison. Ultimately, the overall benefits of SARS‐CoV‐2 vaccination outweigh the potential adverse effects. Therefore, these types of reports should not divert attention from the actual reality.

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