New Theobromine Apoptotic Analogue with Anticancer Potential Targeting the EGFR Protein: Computational and In Vitro Studies

• Ibrahim H. Eissa,
• Reda G. Yousef,
• Eslam B. Elkaeed,
• Aisha A. Alsfouk,
• Dalal Z. Husein,
• Ibrahim M. Ibrahim,
• Ahmed Ismail,
• Hazem Elkady,
• Ahmed M. Metwaly

Affiliations

Ibrahim H. Eissa

Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt

Reda G. Yousef

Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt

Eslam B. Elkaeed

Department of Pharmaceutical Sciences, College of Pharmacy, AlMaarefa University, Riyadh, Saudi Arabia

Aisha A. Alsfouk

Department of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia

Dalal Z. Husein

Chemistry Department, Faculty of Science, New Valley University, El-Kharja, Egypt

Ibrahim M. Ibrahim

Biophysics Department, Faculty of Science, Cairo University, Giza, Egypt

Ahmed Ismail

Biochemistry and Molecular Biology Department, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt

Hazem Elkady

Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt

Ahmed M. Metwaly

Pharmacognosy and Medicinal Plants Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt