Single nucleotide polymorphisms in genes MACC1, RAD18, MMP7 and SDF-1a as prognostic factors in resectable colorectal cancer

Horvat Matej; Potocnik Uros; Repnik Katja; Kavalar Rajko; Zadnik Vesna; Potrc Stojan; Stabuc Borut

doi:10.1515/raon-2016-0043

Radiology and Oncology (May 2017)

Single nucleotide polymorphisms in genes MACC1, RAD18, MMP7 and SDF-1a as prognostic factors in resectable colorectal cancer

Horvat Matej,
Potocnik Uros,
Repnik Katja,
Kavalar Rajko,
Zadnik Vesna,
Potrc Stojan,
Stabuc Borut

Affiliations

Horvat Matej: Department of Oncology, University Medical Centre Maribor, Maribor, Slovenia
Potocnik Uros: Centre for Human Molecular Genetics and Pharmacogenomics, Faculty of Medicine, University of Maribor, Maribor, Slovenia
Repnik Katja: Centre for Human Molecular Genetics and Pharmacogenomics, Faculty of Medicine, University of Maribor, Maribor, Slovenia
Kavalar Rajko: Department of Pathology, University Medical Centre Maribor, Maribor, Slovenia
Zadnik Vesna: Epidemiology and Cancer Registry, Institute of Oncology Ljubljana, Ljubljana, Slovenia
Potrc Stojan: Department of General and Abdominal Surgery, University Medical Centre Maribor, Maribor, Slovenia
Stabuc Borut: Department of Gastroenterology, University Medical Centre Ljubljana, Ljubljana, Slovenia

DOI: https://doi.org/10.1515/raon-2016-0043
Journal volume & issue: Vol. 51, no. 2
pp. 151 – 159

Abstract

Read online

Colorectal cancer (CRC) represents one of the most common malignancies worldwide. Research has indicated that functional gene changes such as single nucleotide polymorphism (SNP) influence carcinogenesis and metastasis and might have an influence on disease relapse. The aim of our study was to evaluate the role of SNPs in selected genes as prognostic markers in resectable CRC.

Published in Radiology and Oncology

ISSN: 1581-3207 (Online)
Publisher: Sciendo
Country of publisher: Slovenia
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine
Website: https://sciendo.com/journal/RAON

About the journal

Abstract

Keywords