Enantioselective nickel-catalyzed dicarbofunctionalization of 3,3,3-trifluoropropene

Yun-Ze Li; Na Rao; Lun An; Xiao-Long Wan; Yanxia Zhang; Xingang Zhang

doi:10.1038/s41467-022-33159-2

Nature Communications (Sep 2022)

Enantioselective nickel-catalyzed dicarbofunctionalization of 3,3,3-trifluoropropene

Yun-Ze Li,
Na Rao,
Lun An,
Xiao-Long Wan,
Yanxia Zhang,
Xingang Zhang

Affiliations

Yun-Ze Li: Key Laboratory of Organofluorine Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences
Na Rao: Key Laboratory of Organofluorine Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences
Lun An: Key Laboratory of Organofluorine Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences
Xiao-Long Wan: Key Laboratory of Organofluorine Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences
Yanxia Zhang: Key Laboratory of Organofluorine Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences
Xingang Zhang: Key Laboratory of Organofluorine Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences

DOI: https://doi.org/10.1038/s41467-022-33159-2
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 9

Abstract

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Strategies for the catalytic asymmetric synthesis of trifluoromethylated compounds remain scarce. Here, the authors report the nickel-catalyzed enantioselective dicarbofunctionalization of 3,3,3-trifluoropropene.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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