Research Note: Effect of a live Salmonella Enteritidis vaccine against Salmonella Pullorum infection in breeder chickens

Peiyong Li; Longzong Guo; Yihao Luan; Wei Zhao; Lulu Cui; Guijuan Hao; Shuhong Sun

Poultry Science (Feb 2023)

Research Note: Effect of a live Salmonella Enteritidis vaccine against Salmonella Pullorum infection in breeder chickens

Peiyong Li,
Longzong Guo,
Yihao Luan,
Wei Zhao,
Lulu Cui,
Guijuan Hao,
Shuhong Sun

Affiliations

Peiyong Li: Department of Preventive Veterinary Medicine, College of Animal Science and Technology, Shandong Agricultural University, Tai'an, China; Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Shandong Agricultural University, Tai'an, China
Longzong Guo: Animal Husbandry and Veterinary Science Research Institute, Yisheng Livestock and Poultry Breeding Co., Ltd., Shandong, China
Yihao Luan: Department of Preventive Veterinary Medicine, College of Animal Science and Technology, Shandong Agricultural University, Tai'an, China; Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Shandong Agricultural University, Tai'an, China
Wei Zhao: Animal Husbandry and Veterinary Science Research Institute, Yisheng Livestock and Poultry Breeding Co., Ltd., Shandong, China
Lulu Cui: Department of Preventive Veterinary Medicine, College of Animal Science and Technology, Shandong Agricultural University, Tai'an, China; Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Shandong Agricultural University, Tai'an, China
Guijuan Hao: Department of Preventive Veterinary Medicine, College of Animal Science and Technology, Shandong Agricultural University, Tai'an, China; Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Shandong Agricultural University, Tai'an, China
Shuhong Sun: Department of Preventive Veterinary Medicine, College of Animal Science and Technology, Shandong Agricultural University, Tai'an, China; Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Shandong Agricultural University, Tai'an, China; Corresponding author:

Journal volume & issue: Vol. 102, no. 2
p. 102308

Abstract

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ABSTRACT: Salmonella Pullorum is one of the most important avian pathogenic bacteria due to widespread outbreaks accompanied by high mortality. It has been demonstrated that the Salmonella Enteritidis live vaccine strain Sm24/Rif12/Ssq is able to induce cross-immunity protection against Salmonella Gallinarum and Salmonella Infantis, however, it is unknown whether this vaccine is effective against Salmonella Pullorum infection. In the present study, the Hubbard parent chickens were orally administrated this vaccine at 1-day-old, 40-day-old, and 131-day-old respectively, and challenged by Salmonella Pullorum at 157-day-old to evaluate the protective effect of the Salmonella Enteritidis live vaccine strain Sm24/Rif12/Ssq. After each vaccination, the vaccine strain could be recovered from cloacal swabs within a week, whereas no vaccine strain was re-isolated from environmental samples throughout the experiment. Vaccination for the breeder chickens with Salmonella Enteritidis Sm24/Rif12/Ssq could relieve swollen liver (P = 0.0066) caused by Salmonella Pullorum infection and decrease Salmonella Pullorum colonization level in spleen (P = 0.0035), whereas no significant difference was found in the bacterial counts of liver, ovary and oviduct of vaccinated chickens. These results suggested that the Salmonella Enteritidis live vaccine strain Sm24/Rif12/Ssq was high safety and effective against Salmonella Pullorum infection to a certain extent.

Published in Poultry Science

ISSN: 0032-5791 (Print); 1525-3171 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Agriculture: Animal culture
Website: https://www.journals.elsevier.com/poultry-science

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