First report of spondylodiscitis caused by Bacillus circulans in an immunocompetent patient: Clinical case and review of the literature
Alessandro Russo,
Umberto Tarantino,
Gabriella d’Ettorre,
Carlo Della Rocca,
Giancarlo Ceccarelli,
Elena Gasbarra,
Mario Venditti,
Riccardo Iundusi
Affiliations
Alessandro Russo
Policlinico “Umberto I”, Department of Public Health and Infectious Diseases, “Sapienza” University of Rome, Italy; Corresponding author at: Department of Public Health and Infectious Diseases, “Sapienza” University of Rome, P.le Aldo Moro 5, 00185, Rome, Italy.
Umberto Tarantino
Department of Orthopaedics and Traumatology, University of Rome “Tor Vergata”, ''Policlinico Tor Vergata'' Foundation, Rome, Italy
Gabriella d’Ettorre
Policlinico “Umberto I”, Department of Public Health and Infectious Diseases, “Sapienza” University of Rome, Italy
Carlo Della Rocca
Department of Medico-Surgical Sciences and Biotechnology, Polo Pontino, “Sapienza” University of Rome, Italy
Giancarlo Ceccarelli
Policlinico “Umberto I”, Department of Public Health and Infectious Diseases, “Sapienza” University of Rome, Italy
Elena Gasbarra
Department of Orthopaedics and Traumatology, University of Rome “Tor Vergata”, ''Policlinico Tor Vergata'' Foundation, Rome, Italy
Mario Venditti
Policlinico “Umberto I”, Department of Public Health and Infectious Diseases, “Sapienza” University of Rome, Italy
Riccardo Iundusi
Department of Orthopaedics and Traumatology, University of Rome “Tor Vergata”, ''Policlinico Tor Vergata'' Foundation, Rome, Italy
Bacillus circulans is mainly considered an opportunistic pathogen in immunocompromised patients. However, many different infections have been described in the literature: bacteremia, abscesses, meningitis, endophthalmitis, and wound infections.We observed a spondylodiscitis caused by Bacillus circulans in an immunocompetent patient. To date, this is the first case reported in literature. Vertebral osteomyelitis represents for clinicians a challenging infection to manage and treat, because of its insidious and indolent course. The diagnosis is frequently difficult and can often be delayed for several months and initially be misdiagnosed and mismanaged. For this reason, the clinical case was described and all published cases of infection caused by Bacillus circulans were reviewed.
