Nature Communications (Mar 2023)
Bacterial outer membrane vesicle based versatile nanosystem boosts the efferocytosis blockade triggered tumor-specific immunity
Abstract
Efferocytosis inhibition leads to the release of immunogenic contents into the tumor microenvironment. Here the authors developed a nanosystem that inhibits MerTK-mediated efferocytosis and captures tumor-associated agents to enhance antitumour immunity.