Pathogens (Mar 2024)

Lipid Profile and Cardiovascular Risk Modification after Hepatitis C Virus Eradication

  • Andrea Pascual-Oliver,
  • Diego Casas-Deza,
  • Carmen Yagüe-Caballero,
  • Jose M. Arbones-Mainar,
  • Vanesa Bernal-Monterde

DOI
https://doi.org/10.3390/pathogens13040278
Journal volume & issue
Vol. 13, no. 4
p. 278

Abstract

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The eradication of the hepatitis C virus (HCV) has revolutionized the hepatology paradigm, halting the progression of advanced liver disease in patients with chronic infection and reducing the risk of hepatocarcinoma. In addition, treatment with direct-acting antivirals can reverse the lipid and carbohydrate abnormalities described in HCV patients. Although HCV eradication may reduce the overall risk of vascular events, it is uncertain whether altered lipid profiles increase the risk of cerebrovascular disease in certain patients. We have conducted a review on HCV and lipid and carbohydrate metabolism, as well as new scientific advances, following the advent of direct-acting antivirals.

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