Interplay of active processes modulates tension and drives phase transition in self-renewing, motor-driven cytoskeletal networks

Abstract

The actin cytoskeleton is a complex network of filaments, cross-linking proteins and motors; although the components are recognised, the behaviour of the network is less understood. Here Mak et al.use a Brownian dynamics model that reveals actin turnover dynamics as a key regulatory mechanism controlling cytoskeletal states.