Nature Communications (Jan 2018)

Architecture of a mammalian glomerular domain revealed by novel volume electroporation using nanoengineered microelectrodes

  • D. Schwarz,
  • M. Kollo,
  • C. Bosch,
  • C. Feinauer,
  • I. Whiteley,
  • T. W. Margrie,
  • T. Cutforth,
  • A. T. Schaefer

DOI
https://doi.org/10.1038/s41467-017-02560-7
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 14

Abstract

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Microcircuit tracing reconstructions often rely on statistical labeling that may not detect all inputs and outputs of a microcircuit. Here the authors employ a novel electroporation approach to densely label neurons and demonstrate its ability to identify sparse anatomical features in the olfactory glomerulus.