Paediatrica Indonesiana (Apr 2009)
Characteristics of HIV.. . infected children born to HIV.. . positive mothers in Cipto Mangunkusumo Hospital between 2002 and 2007
Abstract
Background In 2003, the Joint United Nation Program on HIV/AIDS and the World Health Organisation estimated that there will be 36.2 million people living with HIV /AIDS througout the world by the end of2003, and that 2.1 million of them will be children less than 15 years old. The profile of children with HIV in the Department of Child Health, Cipto Mangunkusumo Hospital has not been studied. Objective To identify the characteristics of HIV-infected children born to HIV-positive mothers, and to evaluate the Prevention Programme for Mother-to-Child Transmission at Cipto Mangunkusumo Hospital. Methods This was a cross-sectional study conducted between March and May 2008 based on medical records. The study population consisted of all mother-child pairs who were admitted between January 2002 and December 2007. Results Between 2002 and 2007,342 children were born to HIV-infected mother, with 201 (58.5%) children contracting HIV The median age of children was 20 months. There were 121 (35.4%) cases involved in prevention of motherto- child transmission. Triple-drug antiretroviral therapy was prescribed to 78.1 o/o children. The most frequent morbidities were chronic diarrhea, wasting syndrome, and oropharyngeal candidiasis. Thirty-six children died; mostly due to sepsis (30.5%) Conclusion The majority of cases of HIV were between 1 and 5 years old. The most frequent morbidities were chronic diarrhea, wasting syndrome, and oropharyngeal candidiasis. Thirty-six children died mostly due to sepsis. The preven- tion program for mother-to-child transmission should be encouraged among pregnant women who are known to be HIV-positive.
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