Bulletin of Emergency and Trauma (Apr 2022)

Heart Rate Variability May Predict the Severity of Appendicitis: A Cross-Sectional Study

  • Ali Mohammad Bananzadeh,
  • Abtin Vahidi,
  • Sarvenaz Salahi,
  • Ali Foroutan,
  • Leila Ghahramani

DOI
https://doi.org/10.30476/beat.2022.91590.1282
Journal volume & issue
Vol. 10, no. 2
pp. 71 – 76

Abstract

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Objective: To evaluate the role of heart rate variability (HRV) in predicting pre-operative severity of appendicitis. Methods: In this cross-sectional study, 171 cases of acute appendicitis who underwent appendectomy were enrolled. Pre-anesthetic pulse rate of included patients were documented while the severity of appendicitis was determined by intra-operative evidences reported by two independent surgeons. Demographic characteristics, laboratory variables, and Alvarado criteria were recorded. Results: The mean age of patients was 28.75±4.21 years; 54% were men. HRV negatively associated the severity of appendix inflammation. A positive association was found between HRV and omental wrapping and Alvarado score (p <0.01). The receiver operating characteristic (ROC) curve analysis demonstrated that HRV could differentiate simple and complicated appendicitis with a sensitivity of 78.5% and specificity of 97.2%. Conclusion: The present findings revealed that HRV may predict the pre-operative severity of appendicitis and help differentiate simple and complicated appendicitis.

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