Organocatalyzed enantioselective desymmetrization of aziridines and epoxides

Abstract

Enantioselective desymmetrization of meso-aziridines and meso-epoxides with various nucleophiles by organocatalysis has emerged as a cutting-edge approach in recent years. This review summarizes the origin and recent developments of enantioselective desymmetrization of meso-aziridines and meso-epoxides in the presence of organocatalysts.

Keywords

• aziridine
• desymmetrization
• enantioselectivity
• epoxide
• organocatalysis