Sensors (May 2015)

Enhanced Sensitive Love Wave Surface Acoustic Wave Sensor Designed for Immunoassay Formats

  • Mihaela Puiu,
  • Ana-Maria Gurban,
  • Lucian Rotariu,
  • Simona Brajnicov,
  • Cristian Viespe,
  • Camelia Bala

DOI
https://doi.org/10.3390/s150510511
Journal volume & issue
Vol. 15, no. 5
pp. 10511 – 10525

Abstract

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We report a Love wave surface acoustic wave (LW-SAW) immunosensor designed for the detection of high molecular weight targets in liquid samples, amenable also for low molecular targets in surface competition assays. We implemented a label-free interaction protocol similar to other surface plasmon resonance bioassays having the advantage of requiring reduced time analysis. The fabricated LW-SAW sensor supports the detection of the target in the nanomolar range, and can be ultimately incorporated in portable devices, suitable for point-of-care testing (POCT) applications.

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