mSphere
(Apr 2021)
Photochromic Fluorophores Enable Imaging of Lowly Expressed Proteins in the Autofluorescent Fungus Candida albicans
Wouter Van Genechten,
Liesbeth Demuyser,
Sam Duwé,
Wim Vandenberg,
Patrick Van Dijck,
Peter Dedecker
Affiliations
Wouter Van Genechten
ORCiD Laboratory of Molecular Cell Biology, Institute of Botany and Microbiology, KU Leuven, Leuven, Belgium
Liesbeth Demuyser
ORCiD Laboratory of Molecular Cell Biology, Institute of Botany and Microbiology, KU Leuven, Leuven, Belgium
Sam Duwé
ORCiD Advanced Optical Microscopy Centre, Biomedical Research Institute (BIOMED), Hasselt University, Hasselt, Belgium
Wim Vandenberg
Lab for Nanobiology, Department of Chemistry, KU Leuven, Leuven, Belgium
Patrick Van Dijck
ORCiD Laboratory of Molecular Cell Biology, Institute of Botany and Microbiology, KU Leuven, Leuven, Belgium
Peter Dedecker
ORCiD Lab for Nanobiology, Department of Chemistry, KU Leuven, Leuven, Belgium
DOI
https://doi.org/10.1128/mSphere.00146-21
Journal volume & issue
Vol. 6,
no. 2
Abstract
Read online
Understanding the spatial and temporal organization of proteins of interest is key to unraveling cellular processes and identifying novel possible antifungal targets. Only a few therapeutic targets have been discovered in Candida albicans
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