Synthesis of Gibberellic Acid Derivatives and Their Effects on Plant Growth
Hao Tian,
Yiren Xu,
Shaojin Liu,
Dingsha Jin,
Jianjun Zhang,
Liusheng Duan,
Weiming Tan
Affiliations
Hao Tian
Engineering Research Centre of Plant Growth Regulators, Ministry of Education, College of Agronomy and Biotechnology, China Agricultural University, Beijing 100193, China
Yiren Xu
Department of Applied Chemistry, College of Science, China Agricultural University, Beijing 100193, China
Shaojin Liu
Engineering Research Centre of Plant Growth Regulators, Ministry of Education, College of Agronomy and Biotechnology, China Agricultural University, Beijing 100193, China
Dingsha Jin
Engineering Research Centre of Plant Growth Regulators, Ministry of Education, College of Agronomy and Biotechnology, China Agricultural University, Beijing 100193, China
Jianjun Zhang
Department of Applied Chemistry, College of Science, China Agricultural University, Beijing 100193, China
Liusheng Duan
Engineering Research Centre of Plant Growth Regulators, Ministry of Education, College of Agronomy and Biotechnology, China Agricultural University, Beijing 100193, China
Weiming Tan
Engineering Research Centre of Plant Growth Regulators, Ministry of Education, College of Agronomy and Biotechnology, China Agricultural University, Beijing 100193, China
A series of novel C-3-OH substituted gibberellin derivatives bearing an amide group were designed and synthesized from the natural product gibberellic acid (GA3). Their activities on the plant growth regulation of rice and Arabidopsis were evaluated in vivo. Among these compounds, 10d and 10f exhibited appreciable inhibitory activities on rice (48.6% at 100 μmol/L) and Arabidopsis (41.4% at 100 μmol/L), respectively. These results provide new insights into the design and synthesis of potential plant growth regulators.
