Frontiers in Chemistry (Aug 2020)

Iron(III)-Mediated Rapid Radical-Type Three-Component Deuteration of Quinoxalinones With Olefins and NaBD4

  • Wanmei Li,
  • Heng Cai,
  • Lin Huang,
  • Lei He,
  • Yilan Zhang,
  • Jun Xu,
  • Pengfei Zhang

DOI
https://doi.org/10.3389/fchem.2020.00606
Journal volume & issue
Vol. 8

Abstract

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Iron(III)-promoted rapid three-component deuteration of quinoxalinones with olefins and NaBD4 is reported for the first time, which provides a novel, economic, and efficient method for the rapid synthesis of deuterated quinoxalinones. In this transformation, a radical pathway is involved according to the results of control experiments.

Keywords