Gold-catalyzed propargylic substitutions: Scope and synthetic developments

Abstract

This personal account summarizes our recent developments in gold-catalyzed direct substitutions on propargylic (allylic, benzylic) alcohols, with various nucleophiles (and bi-nucleophiles) based on the σ- and/or π-acidity of gold(III) complexes. Synthetic developments are also briefly described.

Keywords

• direct substitutions
• gold
• isoxazolines
• propargylic substitutions