Medicinal Product Use Reglandin D-(+) - Cloprostenol, Synthetic Analogue of Prostaglandins F2α Natural Body in Fighting with Anestrus Lute (CL) in Cattle

Abstract

The studies made by us are based on fundamental biological role of prostaglandin modulator of hormonal actions, influxs nerve transmission and cellular ionic exchange. One of the main actions of PGF2α is luteolyse, a process that includes the secretion of progesterone and regression yellow body. PGF2α is a luteolitic for almost species: cow, buffalo, sow, mare, sheep, rabbits, guinea pigs, hamsters and rats, except primates. At present it is considered that PGF2α have their specific receptors, which are fixed and through their model would enable guanidine mono-phosphate or cyclic GMP's Goldberg. The effect of ocitocic luteolitic and pharmacodynamics basis of PGF2α, used in breeding biotechnologies and hormonal therapy. In medicine veterinary prostaglandines are used after 1973. Were injected with 2 ml Reglandin (150 mg D-(+) - cloprostenol) 24 women diagnosed with corpus luteum anestris and 22 females (87.5%) came in to oestrus at a mean of 59 hours, and after an average interval of 70 hours.şi were artificially inseminated (AI) a total of 20 female (83.33%).

Keywords

• biotechnology pregnancy
• luteolyse
• parturition
• prostaglandin