Effects of dietary quercetin on growth, antioxidant capacity, immune response and immune-related gene expression in snakehead fish, Channa argus

Yuxin Kong; Jiaxin Tian; Xiaotian Niu; Min Li; Yidi Kong; Ruoming Li; Xiumei Chen; Guiqin Wang

Aquaculture Reports (Oct 2022)

Effects of dietary quercetin on growth, antioxidant capacity, immune response and immune-related gene expression in snakehead fish, Channa argus

Yuxin Kong,
Jiaxin Tian,
Xiaotian Niu,
Min Li,
Yidi Kong,
Ruoming Li,
Xiumei Chen,
Guiqin Wang

Affiliations

Yuxin Kong: College of Animal Science and Technology, Jilin Agricultural University, Changchun, Jilin 130118, China; Ministry of Education Laboratory of Animal Production and Quality Security, Jilin Agricultural University, Changchun, Jilin 130118, China; Joint Laboratory of Modern Agricultural Technology International Cooperation, Ministry of Education, Jilin Agricultural University, Changchun, Jilin 130118, China; Jilin Provincial Key Laboratory of Animal Nutrition and Feed Science, Jilin Agricultural University, Changchun, Jilin 130118, China
Jiaxin Tian: College of Animal Science and Technology, Jilin Agricultural University, Changchun, Jilin 130118, China; Ministry of Education Laboratory of Animal Production and Quality Security, Jilin Agricultural University, Changchun, Jilin 130118, China; Joint Laboratory of Modern Agricultural Technology International Cooperation, Ministry of Education, Jilin Agricultural University, Changchun, Jilin 130118, China; Jilin Provincial Key Laboratory of Animal Nutrition and Feed Science, Jilin Agricultural University, Changchun, Jilin 130118, China
Xiaotian Niu: College of Animal Science and Technology, Jilin Agricultural University, Changchun, Jilin 130118, China; Ministry of Education Laboratory of Animal Production and Quality Security, Jilin Agricultural University, Changchun, Jilin 130118, China; Joint Laboratory of Modern Agricultural Technology International Cooperation, Ministry of Education, Jilin Agricultural University, Changchun, Jilin 130118, China; Jilin Provincial Key Laboratory of Animal Nutrition and Feed Science, Jilin Agricultural University, Changchun, Jilin 130118, China
Min Li: College of Animal Science and Technology, Jilin Agricultural University, Changchun, Jilin 130118, China; Ministry of Education Laboratory of Animal Production and Quality Security, Jilin Agricultural University, Changchun, Jilin 130118, China; Joint Laboratory of Modern Agricultural Technology International Cooperation, Ministry of Education, Jilin Agricultural University, Changchun, Jilin 130118, China; Jilin Provincial Key Laboratory of Animal Nutrition and Feed Science, Jilin Agricultural University, Changchun, Jilin 130118, China
Yidi Kong: College of Animal Science and Technology, Jilin Agricultural University, Changchun, Jilin 130118, China; Ministry of Education Laboratory of Animal Production and Quality Security, Jilin Agricultural University, Changchun, Jilin 130118, China; Joint Laboratory of Modern Agricultural Technology International Cooperation, Ministry of Education, Jilin Agricultural University, Changchun, Jilin 130118, China; Jilin Provincial Key Laboratory of Animal Nutrition and Feed Science, Jilin Agricultural University, Changchun, Jilin 130118, China
Ruoming Li: College of Animal Science and Technology, Jilin Agricultural University, Changchun, Jilin 130118, China; Ministry of Education Laboratory of Animal Production and Quality Security, Jilin Agricultural University, Changchun, Jilin 130118, China; Joint Laboratory of Modern Agricultural Technology International Cooperation, Ministry of Education, Jilin Agricultural University, Changchun, Jilin 130118, China; Jilin Provincial Key Laboratory of Animal Nutrition and Feed Science, Jilin Agricultural University, Changchun, Jilin 130118, China
Xiumei Chen: College of Animal Science and Technology, Jilin Agricultural University, Changchun, Jilin 130118, China; Ministry of Education Laboratory of Animal Production and Quality Security, Jilin Agricultural University, Changchun, Jilin 130118, China; Joint Laboratory of Modern Agricultural Technology International Cooperation, Ministry of Education, Jilin Agricultural University, Changchun, Jilin 130118, China; Jilin Provincial Key Laboratory of Animal Nutrition and Feed Science, Jilin Agricultural University, Changchun, Jilin 130118, China; Corresponding authors at: College of Animal Science and Technology, Jilin Agricultural University, Changchun, Jilin 130118, China.
Guiqin Wang: College of Animal Science and Technology, Jilin Agricultural University, Changchun, Jilin 130118, China; Ministry of Education Laboratory of Animal Production and Quality Security, Jilin Agricultural University, Changchun, Jilin 130118, China; Joint Laboratory of Modern Agricultural Technology International Cooperation, Ministry of Education, Jilin Agricultural University, Changchun, Jilin 130118, China; Jilin Provincial Key Laboratory of Animal Nutrition and Feed Science, Jilin Agricultural University, Changchun, Jilin 130118, China; Corresponding authors at: College of Animal Science and Technology, Jilin Agricultural University, Changchun, Jilin 130118, China.

Journal volume & issue: Vol. 26
p. 101314

Abstract

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The present study aimed to evaluate the effects of quercetin-supplemented in diet on growth, antioxidant capacity and immune response and immune-related gene expression of Channa argus (C. argus) (initial weight, 24.50 ± 0.24 g). A basal diet was supplemented with quercetin at 0, 150, 300 or 450 mg kg−1 and feed to C. argus 56 days. Weight gain (WG) and specific growth rate (SGR) were significantly increased (P < .05), and feed conversion ratio (FCR) were significantly decreased (P < .05) with the increase of dietary quercetin levels from 0 to 450 mg kg−1. Supplemented quercetin (150, 300 or 450 mg kg−1) significantly enhanced (P < .05) serum or tissues superoxide dismutase (SOD), catalase (CAT), total antioxidant capacity (T-AOC), glutathione S-transferase (GST), glutathione peroxidase (GSH-Px), lysozyme (LZM) activity and complement 3 (C3), complement 4 (C4), immunoglobulin M (IgM) concentration. Meanwhile, quercetin administration significantly up-regulated (P < .05) the expression of immune-related cytokines (interleukin-1β[IL-1β], tumor necrosis factor-α[TNF-α], interleukin-8[IL-8], interleukin-10[IL-10]) in liver, spleen, kidney and intestine of C. argus. These results indicated that dietary supplement quercetin could enhance growth, antioxidant capacity, immune response and regulated immune-related genes expression of C. argus, with greatest effects in C. argus given 300 mg kg−1 quercetin for 56 days.

Published in Aquaculture Reports

ISSN: 2352-5134 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Agriculture: Aquaculture. Fisheries. Angling
Website: http://www.journals.elsevier.com/aquaculture-reports/

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