Microvascular Alteration in COVID-19 Documented by Nailfold Capillaroscopy

Lucrezia Mondini; Paola Confalonieri; Riccardo Pozzan; Luca Ruggero; Liliana Trotta; Selene Lerda; Michael Hughes; Mattia Bellan; Marco Confalonieri; Barbara Ruaro; Francesco Salton; Stefano Tavano

doi:10.3390/diagnostics13111905

Diagnostics (May 2023)

Microvascular Alteration in COVID-19 Documented by Nailfold Capillaroscopy

Lucrezia Mondini,
Paola Confalonieri,
Riccardo Pozzan,
Luca Ruggero,
Liliana Trotta,
Selene Lerda,
Michael Hughes,
Mattia Bellan,
Marco Confalonieri,
Barbara Ruaro,
Francesco Salton,
Stefano Tavano

Affiliations

Lucrezia Mondini: Pulmonology Unit, Department of Medical Surgical and Health Sciences, University Hospital of Cattinara, University of Trieste, 34149 Trieste, Italy
Paola Confalonieri: Pulmonology Unit, Department of Medical Surgical and Health Sciences, University Hospital of Cattinara, University of Trieste, 34149 Trieste, Italy
Riccardo Pozzan: Pulmonology Unit, Department of Medical Surgical and Health Sciences, University Hospital of Cattinara, University of Trieste, 34149 Trieste, Italy
Luca Ruggero: Pulmonology Unit, Department of Medical Surgical and Health Sciences, University Hospital of Cattinara, University of Trieste, 34149 Trieste, Italy
Liliana Trotta: Pulmonology Unit, Department of Medical Surgical and Health Sciences, University Hospital of Cattinara, University of Trieste, 34149 Trieste, Italy
Selene Lerda: Graduate School, University of Milan, 20149 Milano, Italy
Michael Hughes: Division of Musculoskeletal and Dermatological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester & Salford Royal NHS Foundation Trust, Manchester M6 8HD, UK
Mattia Bellan: Department of Translational Medicine, Università del Piemonte Orientale (UPO), 28100 Novara, Italy
Marco Confalonieri: Pulmonology Unit, Department of Medical Surgical and Health Sciences, University Hospital of Cattinara, University of Trieste, 34149 Trieste, Italy
Barbara Ruaro: Pulmonology Unit, Department of Medical Surgical and Health Sciences, University Hospital of Cattinara, University of Trieste, 34149 Trieste, Italy
Francesco Salton: Pulmonology Unit, Department of Medical Surgical and Health Sciences, University Hospital of Cattinara, University of Trieste, 34149 Trieste, Italy
Stefano Tavano: Pulmonology Unit, Department of Medical Surgical and Health Sciences, University Hospital of Cattinara, University of Trieste, 34149 Trieste, Italy

DOI: https://doi.org/10.3390/diagnostics13111905
Journal volume & issue: Vol. 13, no. 11
p. 1905

Abstract

Read online

COVID-19 is a multisystemic disease that mainly affects and causes dysregulation of the endothelium, causing systemic manifestations. A nailfold video capillaroscopy is a safe, easy, and noninvasive method to evaluate microcirculation alteration. In this review, we analyzed the literature available to date regarding the object of nailfold video capillaroscopy (NVC) use in patients with a SARS-CoV-2 infection, both in the acute phase and after discharge. The scientific evidence pointed out the main alterations in capillary circulation shown by NVC, so reviewing the findings of each article allowed us to define and analyze the future prospects and needs for possibly including NVC within the management of patients with COVID-19, both during and after the acute phase.

Published in Diagnostics

ISSN: 2075-4418 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Medicine: Medicine (General)
Website: http://www.mdpi.com/journal/diagnostics

About the journal

Abstract

Keywords