Scientific Reports (Oct 2022)

Deep learning diagnostics for bladder tumor identification and grade prediction using RGB method

  • Jeong Woo Yoo,
  • Kyo Chul Koo,
  • Byung Ha Chung,
  • Sang Yeop Baek,
  • Su Jin Lee,
  • Kyu Hong Park,
  • Kwang Suk Lee

DOI
https://doi.org/10.1038/s41598-022-22797-7
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 8

Abstract

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Abstract We evaluate the diagnostic performance of deep learning artificial intelligence (AI) for bladder cancer, which used white-light images (WLIs) and narrow-band images, and tumor grade prediction of AI based on tumor color using the red/green/blue (RGB) method. This retrospective study analyzed 10,991 cystoscopic images of suspicious bladder tumors using a mask region-based convolutional neural network with a ResNeXt-101-32 × 8d-FPN backbone. The diagnostic performance of AI was evaluated by calculating sensitivity, specificity, and diagnostic accuracy, and its ability to detect cancers was investigated using the dice score coefficient (DSC). Using the support vector machine model, we analyzed differences in tumor colors according to tumor grade using the RGB method. The sensitivity, specificity, diagnostic accuracy and DSC of AI were 95.0%, 93.7%, 94.1% and 74.7%. In WLIs, there were differences in red and blue values according to tumor grade (p 90% for the diagnosis of chronic non-specific inflammation vs. carcinoma in situ using WLIs. The diagnostic performance of the AI-assisted diagnosis was of high quality, and the AI could distinguish the tumor grade based on tumor color.