Nature Communications (Oct 2016)

Structural characterization of antibiotic self-immunity tRNA synthetase in plant tumour biocontrol agent

  • Shaileja Chopra,
  • Andrés Palencia,
  • Cornelia Virus,
  • Sarah Schulwitz,
  • Brenda R. Temple,
  • Stephen Cusack,
  • John Reader

DOI
https://doi.org/10.1038/ncomms12928
Journal volume & issue
Vol. 7, no. 1
pp. 1 – 13

Abstract

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The bacterium Agrobacterium radiobacter K84 secretes an antibiotic that is transported into the plant pathogen A. tumefaciensand processed into the toxin TM84. Here, the authors identify a mechanism whereby the antibiotic-producing microbe resists its own toxin.