Pulmonary light chain deposition disease: Case series and review of the literature

Tomas V. Gonzalez, MD; Anja C. Roden, MD; Brian J. Bartholmai, MD; Rebecca M. Lindell, MD

Radiology Case Reports (Sep 2024)

Pulmonary light chain deposition disease: Case series and review of the literature

Tomas V. Gonzalez, MD,
Anja C. Roden, MD,
Brian J. Bartholmai, MD,
Rebecca M. Lindell, MD

Affiliations

Tomas V. Gonzalez, MD: Department of Radiology, Mayo Clinic, 200 First St. SW, Rochester, MN 55905, USA; Corresponding author.
Anja C. Roden, MD: Department of Pathology, Mayo Clinic, 200 First St. SW, Rochester, MN 55905, USA
Brian J. Bartholmai, MD: Department of Radiology, Mayo Clinic, 200 First St. SW, Rochester, MN 55905, USA
Rebecca M. Lindell, MD: Department of Radiology, Mayo Clinic, 200 First St. SW, Rochester, MN 55905, USA

Journal volume & issue: Vol. 19, no. 9
pp. 3763 – 3769

Abstract

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Pulmonary light chain deposition disease is a rare entity characterized by immunoglobulin deposition within the lung parenchyma with pathologic features distinct from pulmonary amyloidosis. Here, the authors present the clinical presentation, associations, and radiologic features of pulmonary light chain deposition disease in a series of 4 patients as well as discuss the distinctions from amyloidosis. The present case series highlights the frequent presence of both cysts and nodules at CT. Clinically, lymphoma and/or autoimmune disease are often associated.

Published in Radiology Case Reports

ISSN: 1930-0433 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine
Website: https://www.sciencedirect.com/journal/radiology-case-reports

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Abstract

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