Prospective evaluation of septic shock patients in a tertiary care educational university hospital: a series of 1892 cases

Abstract

AIM: We aimed to evaluate the septic shock(SS) cases in terms of mortality and effecting variables for outcomes. BACKGROUND: Despite advancements and the early implementation of targeted therapies,sepsis-related mortality remains high. METHODS: Patients who had SS and consulted to Infectious Diseases between December 2013-September 2023 in our center were followed-up prospectively.Arterial lactate level 2 mg/dL criterion was added as an including criteria for SS according to the latest guidelines.Statistical analysis was performed via Chi-square test, a p value1 pathogen were isolated.One month mortality(OMM) in overall cohort was 76.64% and significantly higher than UTI or intraabdominal infection in the pneumonia SS subgroup(Table,p=0.027).OMM was higher in HASS than in NHASS[79.04%vs.74.64%,p:024].OMM with proven etiology and others were[75.8%vs.77.34%,p:0.427].OMM was significantly higher in lactate>2 subgroup(Table,p1 h after the start of the antibiotics(Table,p<0.014). CONCLUSIONS: The worst outcomes were in pneumonia subgroup.We need more efficient diagnostic as well as and therapeutic tools to decrease the significant mortality.

Keywords

• septic shock
• sespis
• mortality