Nature Communications (Jan 2021)

FSC-Q: a CryoEM map-to-atomic model quality validation based on the local Fourier shell correlation

  • Erney Ramírez-Aportela,
  • David Maluenda,
  • Yunior C. Fonseca,
  • Pablo Conesa,
  • Roberto Marabini,
  • J. Bernard Heymann,
  • Jose Maria Carazo,
  • Carlos Oscar S. Sorzano

DOI
https://doi.org/10.1038/s41467-020-20295-w
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 7

Abstract

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Here, the authors present a cryo-EM validation method for the local analysis of the map-to-model fit and introduce FSC-Q as a quality measure. FSC-Q provides a quantitative estimation of how much of the model is supported by the signal content of the map.