Chinese Journal of Contemporary Neurology and Neurosurgery (Apr 2024)

Diagnosis and treatment of pseudorabies virus infectious encephalitis in human

  • WANG Xiao-juan,
  • JIANG Yu-shu,
  • QIN Ling-zhi,
  • ZHANG Mi-lan,
  • WANG Jia-wei,
  • LI Wei

DOI
https://doi.org/10.3969/j.issn.1672-6731.2024.04.002
Journal volume & issue
Vol. 24, no. 4
pp. 203 – 207

Abstract

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Since 2017, human encephalitis caused by pseudorabies virus (PRV) has been reported in 28 cases in China. The clinical symptoms include fever, headache, seizures, focal neurological loss, disturbance of consciousness, etc.. This disease has the high disability rate and fatality rate. PRV is mainly transmitted through close contact with infected pigs or their excrement, or spread via blood-borne. Patients are mostly practitioners in the live pig industry chain. Early diagnosis and treatment are critical to the prognosis of patients. Therefore, this article reviews the progress on diagnosis and treatment of human encephalitis caused by PRV, in order to improve the clinical diagnosis and treatment of this disease.

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