PLoS ONE (Jan 2021)

COVID-19 prevalence, symptoms, and sociodemographic disparities in infection among insured pregnant women in Northern California.

  • Jennifer L Ames,
  • Assiamira Ferrara,
  • Lyndsay A Avalos,
  • Sylvia E Badon,
  • Mara B Greenberg,
  • Monique M Hedderson,
  • Michael W Kuzniewicz,
  • Yinge Qian,
  • Kelly C Young-Wolff,
  • Ousseny Zerbo,
  • Yeyi Zhu,
  • Lisa A Croen

DOI
https://doi.org/10.1371/journal.pone.0256891
Journal volume & issue
Vol. 16, no. 9
p. e0256891

Abstract

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BackgroundResearch on COVID-19 during pregnancy has mainly focused on women hospitalized for COVID-19 or other reasons during their pregnancy. Little is known about COVID-19 in the general population of pregnant women.ObjectiveTo describe the prevalence of COVID-19, symptoms, consequent healthcare use, and possible sources of COVID-19 exposure among a population-based sample of pregnant women residing in Northern California.MethodsWe analyzed data from 19,458 members of Kaiser Permanente Northern California who were pregnant between January 2020 and April 2021 and responded to an online survey about COVID-19 testing, diagnosis, symptoms, and their experiences during the COVID-19 pandemic. Medical diagnosis of COVID-19 during pregnancy was defined separately by self-report and by documentation in electronic health records (EHR). We examined relationships of COVID-19 with sociodemographic factors, underlying comorbidities, and survey measures of COVID-19-like symptoms, consequent healthcare utilization, and possible COVID-19 exposures.ResultsAmong 19,458 respondents, the crude prevalence of COVID-19 was 2.5% (n = 494) according to self-report and 1.4% (n = 276) according to EHR. After adjustment, the prevalence of self-reported COVID-19 was higher among women aged ConclusionsObserved COVID-19 prevalence differences by sociodemographic and socioeconomic factors underscore social and health inequities among reproductive-aged women. Women with COVID-19 reported unique symptoms and low frequency of hospitalization. Many were not aware of an exposure to someone with COVID-19.