World Allergy Organization Journal (Jan 2009)

Consensus Description of Inclusion and Exclusion Criteria for Clinical Studies of Nonallergic Rhinopathy (NAR), Previously Referred to as Vasomotor Rhinitis (VMR), Nonallergic Rhinitis, and/or Idiopathic Rhinitis

  • Michael A. Kaliner, MD,
  • James N. Baraniuk, MD,
  • Michael S. Benninger, MD,
  • Jonathan A. Bernstein, MD,
  • Phil Lieberman, MD,
  • Eli O. Meltzer, MD,
  • Robert M. Naclerio, MD,
  • Russell A. Settipane, MD,
  • Judith R. Farrar, PhD

Journal volume & issue
Vol. 2, no. 8
pp. 180 – 184

Abstract

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''Nonallergic rhinopathy'' was defined by consensus at a Roundtable conference in December 2008 as ''a chronic nasal condition with symptoms that may be perennial, persistent, intermittent or seasonal and/or elicited by recognized triggers.'' The definition includes a well-recognized set of clinical exposures that lead to the symptoms, predominantly congestion, rhinorrhea, and postnasal drip. These clinical characteristics help to identify patients for participation in clinical trials examining the efficacy of treatments for this important disease. The next step is to establish inclusion and exclusion criteria that will provide a framework for the clinical trials. Agreement on study criteria was obtained at the consensus conference by discussion, counterpoint, and compromise. Keywords: nonallergic vasomotor rhinitis, nonallergic rhinitis, vasomotor rhinitis, idiopathic rhinitis, nonallergic rhinopathy