A difficult-to-treat pleuropulmonary histoplasmosis in a patient with rheumatoid arthritis in Taiwan

Wen-Kai Chu; Un-In Wu; Tai-Fen Lee; Aristine Cheng; Kai-Hsiang Chen; Kuan-Yin Lin; Yee-Chun Chen

Journal of Microbiology, Immunology and Infection (Feb 2023)

A difficult-to-treat pleuropulmonary histoplasmosis in a patient with rheumatoid arthritis in Taiwan

Wen-Kai Chu,
Un-In Wu,
Tai-Fen Lee,
Aristine Cheng,
Kai-Hsiang Chen,
Kuan-Yin Lin,
Yee-Chun Chen

Affiliations

Wen-Kai Chu: Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
Un-In Wu: Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan; Department of Medicine, National Taiwan University Cancer Center, Taipei, Taiwan
Tai-Fen Lee: Department of Laboratory Medicine, National Taiwan University Hospital, Taipei, Taiwan
Aristine Cheng: Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
Kai-Hsiang Chen: Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
Kuan-Yin Lin: Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan; Corresponding author. Department of Internal Medicine, National Taiwan University Hospital, 7 Chung-Shan South Road, Taipei, Taiwan.
Yee-Chun Chen: Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan

Journal volume & issue: Vol. 56, no. 1
pp. 192 – 196

Abstract

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Amphotericin B and itraconazole are the primary agents for treating histoplasmosis. Newer azoles are alternatives for patients refractory to or intolerant of standard therapy. We report an 83-year-old woman with rheumatoid arthritis complicated with pleuropulmonary histoplasmosis who responded to liposomal amphotericin B, but progressed under voriconazole and posaconazole maintenance therapy.

Published in Journal of Microbiology, Immunology and Infection

ISSN: 1684-1182 (Print)
Publisher: Elsevier
Country of publisher: Hong Kong
LCC subjects: Science: Microbiology
Website: https://www.sciencedirect.com/journal/journal-of-microbiology-immunology-and-infection

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