Revista do Colégio Brasileiro de Cirurgiões ()

The role of surgery in the management of women with gestational trophoblastic disease

  • LANA DE LOURDES AGUIAR LIMA,
  • LÍLIAN PADRON,
  • RAPHAEL CÂMARA,
  • SUE YAZAKI SUN,
  • JORGE REZENDE FILHO,
  • ANTÔNIO BRAGA

DOI
https://doi.org/10.1590/0100-69912017001009
Journal volume & issue
Vol. 44, no. 1
pp. 94 – 101

Abstract

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ABSTRACT The Gestational Trophoblastic Disease includes an interrelated group of diseases originating from placental tissue, with distinct behaviors concerning local invasion and metastasis. The high sensitivity of the serial dosages of human chorionic gonadotrophin, combined with advances in chemotherapy treatment, have made gestational trophoblastic neoplasia curable, most often through chemotherapy. However, surgery remains of major importance in the management of patients with gestational trophoblastic disease, improving their prognosis. Surgery is necessary in the control of the disease's complications, such as hemorrhage, and in cases of resistant/relapsed neoplasia. This review discusses the indications and the role of surgical interventions in the management of women with molar pregnancy and gestational trophoblastic neoplasia.

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