BMC Urology (Feb 2010)

Association between gefitinib and hemorrhagic cystitis and severely contracted bladder: a case report

  • Saito Hiroko,
  • Tobiume Motoi,
  • Rosser Charles J,
  • Yamada Yoshiaki,
  • Nakamura Kogenta,
  • Arakawa Maki,
  • Hasegawa Takaaki,
  • Honda Nobuaki

DOI
https://doi.org/10.1186/1471-2490-10-6
Journal volume & issue
Vol. 10, no. 1
p. 6

Abstract

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Abstract Background Gefitinib remains an excellent treatment option for patients with a variety of cancers, including non small cell lung cancer (NSCLC). However, clinicians must be aware of the potential of gefitinib to cause an inflammatory reaction in the skin, lungs and bladder. Case Presentation We present a case on hemorrhagic cystitis and severaly contracted bladder in a patient with NSCLC on gefitinib. Conclusions Further studies are needed to substantiate the association of gefitinib therapy with hemorrhagic cystitis and contracted bladder.