Nature Communications (Feb 2021)
Facilitation of molecular motion to develop turn-on photoacoustic bioprobe for detecting nitric oxide in encephalitis
- Ji Qi,
- Leyan Feng,
- Xiaoyan Zhang,
- Haoke Zhang,
- Liwen Huang,
- Yutong Zhou,
- Zheng Zhao,
- Xingchen Duan,
- Fei Xu,
- Ryan T. K. Kwok,
- Jacky W. Y. Lam,
- Dan Ding,
- Xue Xue,
- Ben Zhong Tang
Affiliations
- Ji Qi
- Department of Chemistry, The Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, Institute for Advanced Study, Department of Chemical and Biological Engineering and Institute of Molecular Functional Materials, The Hong Kong University of Science and Technology
- Leyan Feng
- State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Nankai University, Haihe Education Park
- Xiaoyan Zhang
- State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Bioactive Materials, Ministry of Education, and College of Life Sciences, Nankai University
- Haoke Zhang
- Department of Chemistry, The Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, Institute for Advanced Study, Department of Chemical and Biological Engineering and Institute of Molecular Functional Materials, The Hong Kong University of Science and Technology
- Liwen Huang
- State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Nankai University, Haihe Education Park
- Yutong Zhou
- State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Nankai University, Haihe Education Park
- Zheng Zhao
- Department of Chemistry, The Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, Institute for Advanced Study, Department of Chemical and Biological Engineering and Institute of Molecular Functional Materials, The Hong Kong University of Science and Technology
- Xingchen Duan
- State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Bioactive Materials, Ministry of Education, and College of Life Sciences, Nankai University
- Fei Xu
- State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Nankai University, Haihe Education Park
- Ryan T. K. Kwok
- Department of Chemistry, The Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, Institute for Advanced Study, Department of Chemical and Biological Engineering and Institute of Molecular Functional Materials, The Hong Kong University of Science and Technology
- Jacky W. Y. Lam
- Department of Chemistry, The Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, Institute for Advanced Study, Department of Chemical and Biological Engineering and Institute of Molecular Functional Materials, The Hong Kong University of Science and Technology
- Dan Ding
- State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Bioactive Materials, Ministry of Education, and College of Life Sciences, Nankai University
- Xue Xue
- State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Nankai University, Haihe Education Park
- Ben Zhong Tang
- Department of Chemistry, The Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, Institute for Advanced Study, Department of Chemical and Biological Engineering and Institute of Molecular Functional Materials, The Hong Kong University of Science and Technology
- DOI
- https://doi.org/10.1038/s41467-021-21208-1
- Journal volume & issue
-
Vol. 12,
no. 1
pp. 1 – 11
Abstract
Nitric oxide plays key roles in regulating many pathological processes and it is important to monitor NO and related diseases. Here, the authors report on the development of a molecular motion based NO responsive photoacoustic probe and demonstrate application in detecting encephalitis in vivo.
