Xin yixue (Oct 2023)

Research progress in the application of IL-6 in photodynamic therapy

  • Li Shanshan, Li Jingjing, Mo Xingfan, Wu Minzhi

DOI
https://doi.org/10.3969/j.issn.0253-9802.2023.10.001
Journal volume & issue
Vol. 54, no. 10
pp. 695 – 699

Abstract

Read online

Photodynamic therapy （PDT） is a non-invasive treatment method that combines light sources and photosensitizers. It is currently widely applied in clinical practice to treat acne， genital warts， and multiple tumor diseases. The mechanism of PDT is complex. Researches have found that the efficacy of PDT seems to be closely related to the degree of acute inflammation it causes. IL-6 is a common pro-inflammatory factor that belongs to the category of interleukin （IL）. It is produced by fibroblasts， monocytes/macrophages， and T lymphocytes. It exerts multiple effects on inflammation and immune responses. IL-6 can be induced by PDT in vivo and in vitro. In this article， research progress in the application of IL-6 in PDT was reviewed.

Keywords