New Insights and Enhanced Human Norovirus Cultivation in Human Intestinal Enteroids

Khalil Ettayebi; Victoria R. Tenge; Nicolas W. Cortes-Penfield; Sue E. Crawford; Frederick H. Neill; Xi-Lei Zeng; Xiaomin Yu; B. Vijayalakshmi Ayyar; Douglas Burrin; Sasirekha Ramani; Robert L. Atmar; Mary K. Estes

doi:10.1128/mSphere.01136-20

mSphere (Feb 2021)

New Insights and Enhanced Human Norovirus Cultivation in Human Intestinal Enteroids

Khalil Ettayebi,
Victoria R. Tenge,
Nicolas W. Cortes-Penfield,
Sue E. Crawford,
Frederick H. Neill,
Xi-Lei Zeng,
Xiaomin Yu,
B. Vijayalakshmi Ayyar,
Douglas Burrin,
Sasirekha Ramani,
Robert L. Atmar,
Mary K. Estes

Affiliations

Khalil Ettayebi: ORCiD; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA
Victoria R. Tenge: ORCiD; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA
Nicolas W. Cortes-Penfield: Department of Medicine, Baylor College of Medicine, Houston, Texas, USA
Sue E. Crawford: Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA
Frederick H. Neill: Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA
Xi-Lei Zeng: Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA
Xiaomin Yu: Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA
B. Vijayalakshmi Ayyar: ORCiD; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA
Douglas Burrin: Section of Gastroenterology, Hematology and Nutrition, Department of Pediatrics, Baylor College of Medicine, and USDA/ARS Children’s Nutrition Research Center, Houston, Texas, USA
Sasirekha Ramani: ORCiD; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA
Robert L. Atmar: ORCiD; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA
Mary K. Estes: ORCiD; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA

DOI: https://doi.org/10.1128/mSphere.01136-20
Journal volume & issue: Vol. 6, no. 1

Abstract

Read online

Human noroviruses (HuNoVs) are highly contagious and cause acute and sporadic diarrheal illness in all age groups. In addition, chronic infections occur in immunocompromised cancer and transplant patients.

Published in mSphere

ISSN: 2379-5042 (Online)
Publisher: American Society for Microbiology
Country of publisher: United States
LCC subjects: Science: Microbiology
Website: https://journals.asm.org/journal/msphere

About the journal