Nature Communications (Apr 2019)

Muscle functions as a connective tissue and source of extracellular matrix in planarians

  • Lauren E. Cote,
  • Eric Simental,
  • Peter W. Reddien

DOI
https://doi.org/10.1038/s41467-019-09539-6
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 13

Abstract

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How the cellular source of positional information compares across regenerative animals is unclear. Here, the authors find that planarian muscle, which harbours positional information, acts as a connective tissue by being a major site of matrisome gene expression and by maintaining tissue architecture.