Nature Communications (Oct 2019)

Upconversion superballs for programmable photoactivation of therapeutics

  • Zhen Zhang,
  • Muthu Kumara Gnanasammandhan Jayakumar,
  • Xiang Zheng,
  • Swati Shikha,
  • Yi Zhang,
  • Akshaya Bansal,
  • Dennis J. J. Poon,
  • Pek Lim Chu,
  • Eugenia L. L. Yeo,
  • Melvin L. K. Chua,
  • Soo Khee Chee,
  • Yong Zhang

DOI
https://doi.org/10.1038/s41467-019-12506-w
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 12

Abstract

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The synthesis of nanoparticles capable of orthogonal photo-activity is complex. Here, the authors report on an assembly process of two distinct nanoparticles into composite nanoparticles as a simple method and report on the application in photodynamic therapy and siRNA delivery in tumour therapy.